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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC6
All Species:
23.64
Human Site:
S1059
Identified Species:
47.27
UniProt:
Q96SB8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB8
NP_001135758.1
1091
126326
S1059
S
M
S
S
L
P
S
S
K
L
I
R
I
L
R
Chimpanzee
Pan troglodytes
XP_001136387
1091
126280
S1059
S
M
S
S
L
P
S
S
K
L
I
R
I
L
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532882
1606
180795
S1574
S
M
S
S
L
P
S
S
K
L
I
R
I
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q924W5
1097
127179
S1065
S
M
S
S
L
P
S
S
K
L
I
R
I
L
R
Rat
Rattus norvegicus
NP_001101484
1097
127259
S1065
S
M
S
S
L
P
S
S
K
L
I
R
I
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505822
579
67328
L548
L
R
N
F
S
Q
H
L
R
D
L
K
I
K
R
Chicken
Gallus gallus
XP_419962
1096
127736
L1063
T
P
Q
S
M
S
F
L
P
V
S
S
R
I
R
Frog
Xenopus laevis
Q6P9I7
1128
130494
T1097
N
M
S
S
L
P
S
T
S
L
V
R
I
L
R
Zebra Danio
Brachydanio rerio
NP_001121806
1090
126266
S1059
F
L
T
P
Q
N
M
S
S
L
P
I
N
S
L
Tiger Blowfish
Takifugu rubipres
Q802R8
1090
124790
M1059
I
F
L
T
P
Q
S
M
S
S
L
P
E
C
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794820
1236
142110
K1202
D
M
S
K
I
T
P
K
P
S
V
R
I
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12749
1114
127990
P1082
T
Q
T
I
I
I
T
P
Q
D
I
G
K
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
63.3
N.A.
90
90.4
N.A.
38.1
59.7
60.5
51.4
45.9
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
100
N.A.
66.1
N.A.
96.3
96.2
N.A.
44
77.9
76.7
70.3
67
N.A.
N.A.
N.A.
50.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
13.3
73.3
13.3
13.3
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
40
40
93.3
26.6
26.6
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
9
9
0
9
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
9
17
9
0
0
0
0
50
9
67
17
0
% I
% Lys:
0
0
0
9
0
0
0
9
42
0
0
9
9
9
0
% K
% Leu:
9
9
9
0
50
0
0
17
0
59
17
0
0
50
9
% L
% Met:
0
59
0
0
9
0
9
9
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
9
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
9
0
9
9
50
9
9
17
0
9
9
0
0
0
% P
% Gln:
0
9
9
0
9
17
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
9
0
0
59
9
0
84
% R
% Ser:
42
0
59
59
9
9
59
50
25
17
9
9
0
9
0
% S
% Thr:
17
0
17
9
0
9
9
9
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _